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LancetClaw AnswersUpdated Mar 17, 2026

What is the Newcastle-Ottawa Scale?

Short answer

The Newcastle-Ottawa Scale (NOS) is a quality assessment tool for non-randomised studies (cohort and case-control) used in systematic reviews. It scores studies on a star system across three domains: selection (4 stars max), comparability (2 stars max), and outcome/exposure (3 stars max) for a maximum of 9 stars. Scores of 7+ are generally considered high quality.

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Action Snapshot

  • Execution steps5
  • Failure checks3
  • FAQ entries2

Quick Actions

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Execution Steps

  1. 1Determine if your study is a cohort or case-control design (NOS has separate scales).
  2. 2Score the selection domain: representativeness, selection of controls, ascertainment of exposure.
  3. 3Score the comparability domain: comparability of cohorts based on design or analysis.
  4. 4Score the outcome domain: assessment of outcome, length and adequacy of follow-up.
  5. 5Sum the stars for an overall quality score (max 9).

Prompt Template

Help me score this cohort study using the Newcastle-Ottawa Scale. The study examined [exposure] and [outcome] in [population] over [time period].

Common Failure Points

  • Using the cohort scale for case-control studies (or vice versa)
  • Not pre-specifying which confounders to assess in the comparability domain
  • Treating the star count as an absolute quality measure without considering domain-specific patterns

FAQ

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